An ASC2025 Workshop: Introduction to Response Adaptive Randomization

📅 30 November 2025 11AM - 5 PM (AWST) | 📍 In-person

This full-day course provides a practical, hands-on introduction to Response Adaptive Randomization (RAR), starting with theoretical foundations before moving into real-world applications.

The course will cover:

• How to implement and compare different RAR designs in practice

• Key considerations for targeting optimal allocation proportions

• Advanced methodological topics such as early stopping and statistical estimation

• Applications in rare disease settings and dose-finding studies

• A detailed case study of the ARREST trial

Through a mix of lectures and practical sessions (including use of an R Shiny app), participants will gain the skills and knowledge to understand, implement, and critically evaluate RAR designs. This course is ideal for statisticians, methodologists, and clinical trial professionals seeking to enhance their expertise in innovative trial design.

Presenter: A/Prof Sofia S. Villar - MRC Biostatistics Unit, Cambridge, UK